Figure 1.

Impact of varying vaccine characteristics on the incremental cost-effectiveness ratio (ICER) from the healthcare system perspective when vaccinating each target population (women of childbearing age, school-aged children, young adults, and everyone) for a Zika outbreak starting 5 years after vaccination in Honduras with a 20% attack rate (A), Brazil with a 2% attack rate (B), and Puerto Rico with a 2% attack rate (C). An ICER of 0 indicates the strategy would be economically dominant (provides cost savings and health benefits). ICERs greater than $50000 per disability-adjusted life-year (DALY) averted and $35000 per DALY averted are not shown for Brazil and Puerto Rico, respectively.