Table 1.
Diffusion tensor tractography studies of central post-stroke pain caused by the spinothalamic tract injury.
| Authors | Publication year | Number of patients | Duration to DTI | Pathology and lesion location | DTT analysis method and results | Limitations |
|---|---|---|---|---|---|---|
| Seghier et al. (23) | 2005 | 1 | 4–5 years | Intracerebral hemorrhage (thalamus and internal capsule) | Configuration (fiber density↓) | Uncertain ROIs, case report, no reliability for DTT |
| Goto et al. (19) | 2008 | 17 | 5.1 years (1–8.8 years) | Stroke (supratentorial area) | Higher delineration ratio: rTMS effective | Not pure STT, no reliability for DTT |
| Hong et al. (24) | 2010 | 30 | 20 months (5–48 months) | Intracerebral hemorrhage (corona radiata and basal ganglia) | Laterality index of DTT parameters (FA, MD, TV↓) | No reliability for DTT |
| Hong et al. (29) | 2012 | 52 | 18.8 months (5–46 months) | Intracerebral hemorrhage (corona radiata, basal ganglia, and thalamus) | Configuration (impaired integrity), DTT parameters (FA, MD, TV↓) | Simple analysis using integrity of STT, no reliability for DTT |
| Jang et al. (30) | 2017 | 5 | 11 days (10–13 days) | Cerebral infarct (corona radiata, thalamus, and pre- and post-central gyrus) | DTT parameters (FA↓, MD↑, TV↓) | Case series, no reliability for DTT |
| Jang et al. (31) | 2018 | 1 | 2 weeks 14 months | Intracerebral hemorrhage (thalamus) | Configuration (partial tearing and thinning) | Case report, no reliability for DTT |
DTT, diffusion tensor tractography; FA, fractional anisotropy; MD, mean diffusivity; TV, tract volume; rTMS, repetitive transcranial magnetic stimulation; ROIs, regions of interest; STT, spinothalamic tract.