Figure 1.

IL‐2 production associates with asthma severity. A, IL‐2 production was inversely correlated with FEV₁ (% predicted) and (B) positively correlated with total daily dose of inhaled corticosteroid (fluticasone equivalent μg/day). IL‐2 production was positively correlated with the proportion of circulating (C) CD4⁺ T cells and (D) Th2 cells. E, Proportion of circulating Th2 cells were positively correlated with total daily dose of inhaled corticosteroid. FEV1, forced expiratory volume in 1 second; ICS, inhaled corticosteroid; IL‐2, interleukin 2; Th2, T helper cell