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. 2019 Aug 8;15:1744806919867842. doi: 10.1177/1744806919867842

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© The Author(s) 2019

Creative Commons CC BY: This article is distributed under the terms of the Creative Commons Attribution 4.0 License (http://www.creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 8. — Compound 48/80-induced β-hexosaminidase release from untreated mast cells were no different from those of TAK-242 pre-treated mast cells, suggesting that TLR4 does not influence 48/80-mediated mast cell degranulation. Bar graph represents percentage of β-hexosaminidase release from murine mast cells following treatments with different concentrations of TAK-242 (50 nM, 500 nM, and 1000 nM) 1 h prior to compound 48/80 (10 μg/ml), N = 8. ***P < 0.001 as compared to PBS. ns: non-significant as compared to compound 48/80 treated group; PBS: phosphate-buffered saline.