Fig. 2.
Relationship between medial hypertrophy of intra-acinar pulmonary arteries (intraoperative lung biopsy) and response to inhaled NO during preoperative cardiac catheterization. The mean wall thickness of arteries present in the biopsy specimen was calculated and expressed as Z score using normal values for age according to Haworth and Hislop.19 In the upper and middle panels, changes in PVR and PVR/SVR as a result of NO administration are expressed as percent reduction from baseline. The lower panels show absolute values for PVR/SVR registered at 10 min of NO inhalation.