Figure 2.
Antibody complexes with allergens. A) VH (blue) in complex with lysozyme (Gal d 4, orange) rendered as cartoon diagrams with the surface of lysozyme shown semi-transparent. CDR3 of the VH is highlighted in pink in the lysozyme active site cleft. B) Phl p 7 bound to 101.1F10. Two Phl p 7 molecules are rendered as semi-transparent surfaces and bound Ca2+ ions are shown as spheres. Arg 7 of Phl p 7 is labeled. Two 101.1F10 molecules are rendered as cartoon secondary structures in green and cyan, while CDR L2 is shown with white stick renderings. The Classical (canonical) and Noncanonical antibody interacting regions are labeled.