Fig. 4.
Influence of the K+ channel blockers on the vasorelaxant response to Ang-(1–7) in the renal artery. Linear plots of percent vasorelaxation (%) versus the log dose of Ang-(1–7) show the effects of glibenclamide (GLI, 10−5M) or iberiotoxin(IBE, 5 × 10−8M) on Ang-(1–7)-induced vasodilation of the isolated renal artery of the rat. Data are mean ± SEM (n = 8–10 per group; see Table 2) compared to Ang-(1–7) alone by ANOVA with Dunnett’s post hoc test. *P < 0.05 versus Ang-(1–7) from 10−11 to 3 × 10−6M; #P<0.05 versus Ang-(1–7) from 10−7 to 3 × 10−6M.