Competition of 125I-[Sar1,Thr8]-Ang II binding by various angiotensin receptor antagonists in AR42J cell membranes. Competition curves for percent binding (%) of 125I-[Sar1,Thre8]-Ang II and the log dose of various competitors that include the non-selective antagonist [Sar1,Thre8]-AngII (Sar), the AT2 antagonist PD123319 (PD), Ang-(1–7) (Ang 7) the Mas receptor antagonists [D-Ala7]-Ang-(1–7) (DALA) and [D-Pro7]-Ang-(1–7) (DPRO). Data are mean ± SEM (n = 3). Competition curves were constructed in Prism 6 by non-linear regression using a one site fit.