Table 2.

Influence of Signaling Inhibitors on Ang-(1–7)-Dependent Vasorelaxation of the Isolated Renal Artery.

Groups	Maximal Response (%)	N
Control	42.4 ± 5.8	10
Denuded	9.8 ± 3.5*	4
l-NAME	13.4 ± 2.0*	6
Indomethacin	23.7 ± 9.0	7
l-NAME/Indomethacin	20.5 ± 3.0*	8
ODQ	10.0 ± 2.1*	8
HOE140	14.0 ± 7.0*	9
HOE/l-NAME	10.2s ± 3.8*	9
Iberiotoxin	22.1 ± 7.4*	8
Glibenclamide	22.3 ± 2.3*	8

Maximal vasorelaxation response to Ang-(1–7) alone or in the presence of various signaling inhibitors.

Data are the means ± SEM (N = 4–10) analyzed by one-way ANOVA with Dunnett’s post hoc test;

^*P < 0.05 vs. Ang-(1–7) as control.