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(A) Induction of ventricular flutter (CL 150 ms) in a patient with KCNH2 mutation (N588K; SQTS1) before starting HQ treatment. (B and C) After the application of HQ, the QTc interval (corrected by Bazett formula) was significantly increased in SQTS1 and SQTS5 patients without induction of arrhythmias in the electrophysiology study.
