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(A) Increased QTc interval after HQ treatment in the presence of SQTS1. (B) QTc interval was significantly prolonged in the presence of N588K mutation of KCNH2 after HQ treatment. (C) QTc interval was not significantly prolonged after HQ use in the presence of KCNH2 mutation in T618I. (D) Effect of HQ on QTc interval in the presence of SQTS2 to SQTS5.
