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. 2019 Aug 9;19:791. doi: 10.1186/s12885-019-6014-5

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Oct4, Egr1, and OPN are overexpressed in lung cancer and Egr1 expression is correlated with shorter survival. a, Representative staining for Oct4, Egr1, and OPN in human lung tumors graded as low and high expression. b, Numbers of tumors expressing high or low levels of Egr1 in tumors with high or low Oct4 expression. c. Numbers of tumors expressing high or low levels of OPN in tumors with high or low Egr1 expression. d, Tumor recurrence rates between high- and low- expression of Oct4, Egr1, and OPN in lung cancer patients, none of them reached statistical significance (Oct4: p = 0.273; Egr1: 0.261; OPN: 0.253). e-g, Kaplan-Meier curves for disease-free survivals in patients with high (red line) and low (black line) Oct4 (e), Egr1 (f), and OPN (g) expression