Table 1.

Flow chart of the study: time points and the assessed dimensions at the time points

Outcome dimensions and time points	Time points
	− 4 to − 1 weeksa	− 1 week	Week 0	Week 3	Week 6
Diagnosis and surgery	X
Chemotherapy and/or radiotherapy at the same time			X X
Patient’s eligibility is checked		X
Signed written informed consent
Randomization		X
Assessment
Cardiovascular performance (6MWT) and grip strength			X	X	X
Psychological functioning			X	X	X
Start study interventions			X
Interventions			X X
Study end					X

6MWT 6-min walking test, X this dimension is assessed; blue arrow, the time point from one period to the next

^a− 4 to − 1 weeks, 4 weeks to 1 week of pre-treatment period