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Cytotoxicity of oxaliplatin, mAb (anti-c-Met IgG), and ADC (anti-c-Met IgG-OXA) to the HepG2 and shMet-HepG2 cell lines.
| IC50 (μmol) | Oxaliplatin | Anti-c-Met IgG | Anti-c-Met IgG-OXA |
|---|---|---|---|
| HepG2 | 44.96 ± 1.05 | >1,000 | 10.34 ± 0.84 |
| ShMet-HepG2 | 33.10 ± 1.92 | >1,000 | >1,000 |
