Table 1.

Overlap of 90 pigmentation and melanoma GWAS SNPs with H3K27ac-marked regions and with SOX10 ChIP binding

Genomic regions	Overlapping GWAS SNPs	GWAS-associated phenotypes
H3K27ac-marked regions (DMSO or AZD6244)	70	Hair color, eye color, skin pigmentation, cutaneous melanoma, nevus, freckles, suntan, sunburn, vitiligo
H3K27ac differentially acetylated regions	52	Hair color, eye color, skin pigmentation, cutaneous melanoma, nevus, freckles, suntan, vitiligo
H3K27ac super-enhancers (DMSO or AZD6244)	46	Hair color, eye color, skin pigmentation, cutaneous melanoma, nevus, freckles, suntan, vitiligo
SOX10 ChIP (DMSO or AZD6244)	8	Hair color, eye color, skin pigmentation, cutaneous melanoma, freckles, suntan, sunburn, vitiligo