Table 4.
Haplotype block analysis of metabolic and anthropometric changes after vitamin D supplementation (4000 IU/day) for 12 weeks
| Variables | H1 | H2 | H3 | H4 | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Global-Stat | P Value* | FDR P Value** | Global-Stat | P Value* | FDR P Value** | Global-Stat | P Value* | FDR P Value** | Global-Stat | P Value* | FDR P Value** | |
| BMI, Kg/m2 | 18.87 | 0.27 | 0.65 | 3.89 | 0.79 | 0.92 | 9.94 | 0.19 | 0.65 | 5.61 | 0.46 | 0.72 |
| WC, cm | 10.66 | 0.82 | 0.92 | 5.47 | 0.60 | 0.86 | 8.05 | 0.32 | 0.65 | 6.73 | 0.34 | 0.65 |
| HC, cm | 26.97 | 0.04 | 0.25 | 4.68 | 0.69 | 0.92 | 7.33 | 0.39 | 0.66 | 2.88 | 0.82 | 0.92 |
| Fat mass, cm | 17.33 | 0.63 | 0.86 | 7.66 | 0.36 | 0.65 | 3.96 | 0.78 | 0.92 | 8.26 | 0.21 | 0.65 |
| Muscle mass, (%) | 13.50 | 0.85 | 0.92 | 4.28 | 0.74 | 0.92 | 7.60 | 0.36 | 0.65 | 11.36 | 0.07 | 0.34 |
| Trunk fat, (%) | 17.50 | 0.62 | 0.86 | 9.01 | 0.25 | 0.65 | 2.64 | 0.91 | 0.93 | 7.13 | 0.30 | 0.65 |
| Visceral fat | 45.46 | < 0.001 | < 0.001 | 3.58 | 0.82 | 0.92 | 79.69 | < 0.001 | < 0.001 | 7.82 | 0.25 | 0.65 |
| LDL, mg/dL | 18.90 | 0.27 | 0.65 | 7.53 | 0.37 | 0.65 | 9.37 | 0.22 | 0.65 | 9.20 | 0.16 | 0.64 |
| HDL, mg/dL | 27.83 | 0.03 | 0.22 | 16.43 | 0.02 | 0.22 | 5.74 | 0.56 | 0.84 | 9.24 | 0.16 | 0.64 |
| TC, mg/dL | 15.83 | 0.46 | 0.72 | 15.02 | 0.03 | 0.22 | 2.90 | 0.89 | 0.93 | 6.41 | 0.37 | 0.65 |
| TG, mg/dL | −53.73 | 1 | 1.00 | 3.24 | 0.86 | 0.92 | 13.06 | 0.07 | 0.34 | 13.48 | 0.03 | 0.22 |
BMI Body mass index, WC Waist circumference, HC Hip circumference, TC Total cholesterol, LDL-C Low-density lipoprotein cholesterol, HDL-C High-density lipoprotein cholesterol, TG Triglycerides
H1, Cdx2, FokI, BsmI, ApaI, TaqI; H2, Cdx2, FokI, BsmI, H3, BsmI, ApaI, TaqI; H4, FokI, BsmI, ApaI
*All values were adjusted for age, baseline 25-hydroxy vitamin D (25(OH)D), energy intake, fat intake and physical activity
**FDR P values were obtained using the false-discovery rate (FDR) methods