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. 2019 Aug 9;12:75. doi: 10.1186/s13048-019-0550-0

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — The expression of the CN in ovarian cancer with later-stage or early-stage. The different subtypes of human ovarian cancer, including (a) total type, (b) clear cell carcinoma, (c) serous carcinoma, and (d) papillary serous cystadenocarcinoma, were examined the expression of CN via IHC staining (CN-positive percentage). The results were presented as the percentage-change in CN expression of later-stage tumor tissue (stage III~IV) relative to that in early-stage tumor tissue (stage I~II). The CN expression of serous carcinoma was significantly higher in later-stage tumor tissue than in early-stage tumor tissue (p < 0.05)