Table 2.
Distributions of resistance and virulence-related genes in GBS recovered from neonates and pregnant women, respectively
| Resistance/virulence-related genes | No. of isolates | |||
|---|---|---|---|---|
| EOGBS | LOGBS | NCGBS | MCGBS | |
| ERY and CLI resistance genesa | ||||
| ermB | 4 | 8 | 8 | 11 |
| mefA/E | 1 | 10 | ||
| lnuB | 1 | |||
| ermB, mefA/E | 1 | 2 | 6d | |
| ermB, lnuB | 3 | 6 | 2 | 5 |
| mefA/E, lnuB | 1 | 2 | ||
| mefA/E, lnuD | 6 | |||
| ermB, mefA/E, lnuB | 2 | |||
| ermTR, mefA/E | 1d | |||
| TET resistance genesb | ||||
| TetO | 1 | 4 | 5 | 9 |
| TetM | 1 | 37 | ||
| TetS | 1 | 1 | ||
| TetO, TetM | 8 | 11 | 4 | 2 |
| TetM, TetS | 1 | |||
| TetO, TetM, TetL | 1 | 2 | 1 | |
| TetO, TetM, TetK | 1 | |||
| Virulence-related genesc | ||||
| hylB | 4 | |||
| hylB, lmb | 1 | 2 | 4 | |
| hylB, scpB | 1 | |||
| hylB, lmb, scpB | 9 | 15 | 3 | 44 |
| hylB, lmb, bca | 1 | |||
| hylB, lmb, scpB, bac | 1 | 4 | 4 | |
| hylB, lmb, scpB, bac, bca | 2 | 1 | 2 | |
ERY erythromycin, CLI clindamycin, TET tetracycline EOGBS early-onset GBS, LOGBS late-onset GBS, NCGBS neonatal colonizing GBS, MCGBS maternal colonizing GBS
a 36 and 44 isolates of erythromycin and/or clindamycin resistant/intermediate GBS were detected in neonates and pregnant women, respectively
b 39 and 51 isolates of tetracycline resistant GBS were detected in neonates and pregnant women, respectively
c 41 and 57 isolates of GBS were detected in neonates and pregnant women, respectively
d Inducible clindamycin resistance was detected in GBS isolate for each one, respectively