Table 3.
Phenotype and molecular characterization of various serotype-ST/CC GBS recovered from infected neonates (no. of isolates)
| CPS type-ST/CC | Resistance profile | ERY and CLI resistance gene | TET resistance gene | Virulence-related gene | Culture-confirmed Infection |
|---|---|---|---|---|---|
| III-ST17/CC17 (18) | ERYRCLIR (16), TETR (18) | ermB (16), mefA/E (2), lnuB (5) | tetO (18), tetM (13), tetL (1) | hylB (18), lmb (18), scpB (17) | SE (16), BA (1), OM (1) |
| III-ST19/CC19 (4) | ERYRCLIR (3), TETR (4) | ermB (2), mefA/E (1), lnuB (3) | tetO (3), tetM (4), tetL (1) | hylB (4), lmb (4), scpB (4) | SE (4) |
| III-ST171/CC17 (1) | ERYRCLIR (1), TETR (1) | ermB (1) | tetO (1), tetM (1) | hylB (1), lmb (1), scpB (1) | SE (1) |
| Ib-ST12/CC10 (3) | ERYRCLIR (3), TETR (3) | ermB (3), lnuB (2) | tetO (3), tetM (3) | hylB (3), lmb (3), scpB (3), bac (3), bca (2) | SE (2), OM (1) |
| Ib-ST10/CC10 (1) | ERYRCLIR (1) | ermB (1) | none | hylB (1), lmb (1), scpB (1), bac (1), bca (1) | SE (1) |
| Ia-ST23/CC23 (1) | TETR (1) | none | tetO (1), tetM (1) | hylB (1), lmb (1), scpB (1) | SE (1) |
| V-ST456/CC19 (1) | ERYRCLIR (1), TETR (1) | ermB (1), mefA/E (1) | tetO (1), tetM (1), tetL (1) | hylB (1), lmb (1), scpB (1) | OM (1) |
CPS capsular polysaccharide, ST sequence type, CC clonal complex, R resistant, ERY erythromycin, CLI clindamycin, TET tetracycline, SE sepsis, BA bacteremia, OM omphalitis