Table 4.

Cox proportional hazard analysis of progression-free survival and overall survival in papillary thyroid carcinoma.

	Progression free survival						Overall survival
	Univariate analysis			Multivariate analysis			Univariate analysis			Multivariate analysis
	Odds ratio	95% CI	p-value	Odds ratio	95% CI	p-value	Odds ratio	95% CI	p-value	Odds ratio	95% CI	p-value
Age ≥ 45 years	1.358	0.801–2.302	0.256				14.244	1.901–106.704	0.010
Male sex	1.690	0.971–2.942	0.064				0.678	0.197–2.326	0.536
Diameter ≥ 2.0 cm	1.567	0.925–2.656	0.095				2.299	0.934–5.659	0.070
T stage	1.317	0.828–2.096	0.245				1.752	0.824–3.723	0.145
N stage	4.253	2.018–8.967	<0.001	2.953	1.286–6.783	0.011	1.786	0.643–4.966	0.266
Cancer stage	2.487	1.492–4.146	<0.001	1.898	1.050–3.430	0.034	6.839	2.462–19.000	<0.001	6.839	2.462–19.000	<0.001
Infiltrative margin	1.678	0.721–3.904	0.230				3.416	0.456–25.607	0.232
Extrathyroidal involvement	2.025	1.026–3.998	0.042				0.860	0.327–2.262	0.759
CD15 positivity	1.943	1.155–3.267	0.012	1.929	1.132–3.288	0.016	1.616	0.636–4.109	0.313
CD24 positivity	n/a	n/a	n/a				n/a	n/a	n/a
CD44 positivity	2.917	1.167–7.294	0.022	2.960	1.137–7.704	0.026	0.999	0.331–3.016	0.999
CD166 positivity	8.056	4.810–13.494	<0.0001	7.485	4.333–12.930	<0.001	0.428	0.057–3.212	0.410
ALDH1A1 positivity	7.236	3.105–16.861	<0.001	3.736	1.467–9.515	0.006	n/a	n/a	n/a

CI, Confidence interval; n/a, not applicable. Bold values indicate statistically significant (p <0.05).