Table 3.

Gene ontology analysis of human breast CAF gene sets

Gene ontology terms/biological process	p-value
CAFs—upregulated genes
Mitotic cell cycle	3.40E-30
M phase	2.40E-26
Regulation of cell cycle	8.60E-14
Organelle organization and biogenesis	8.10E-09
Sister chromatid segregation	9.60E-06
Establishment of organelle localization	1.90E-05
DNA repair	1.10E-04
Chromosome localization	3.80E-04
Interphase	6.00E-04
Biopolymer metabolism	2.30E-03
Establishment of cellular localization	5.10E-03
Cellular localization	5.40E-03
Cytokinesis	8.20E-03
CAFs—downregulated genes
Cell-matrix adhesion	1.50E-02