Table 2-.

qRT-PCR analysis of neuroblastoma cells transfected with miR-control vector, miR-455-3p vector, mutant APP cDNA and their mRNA fold change calculations relative to miR-control vector

		(Fold change-mRNA/β-actin)
	Genes	miR-455-3p vector	Mutant APP cDNA	Mutant APP+miR-455-3p	Mutant APP+miR-control
Mitochondrial biogenesis genes	PGC1α	4.24**	−1.8*	3.64**	−1.7*
	NR.F1	3.18**	−1.4	2.48*	−4.81**
	NRF2	3.2*	−1.59*	2.43*	−1.25*
	TFAM	2.6*	−1.4*	2.68*	−4.49**
Synaptic genes	Synaptophysin	2.5*	−2.44*	2*	−1.45*
	PSD95	3.25*	−3.29**	2.78*	−2.37**
Mitochondrial fission genes	DRP1	− 1.42*	2.36*	− 1.18	2.43*
	FIS1	− 1.37*	1.89*	− 1.17	1.61*
Mitochondrial fusion genes	OPA1	1.59*	− 1.93*	1.85*	− 1.4*
	Mfn1	1.92*	− 1.46*	1.48*	− 1.76*
	Mfn2	2.01*	− 1.14	1.93*	− 1.19