Table 3.
Correlations of GLS H-score in a human breast tumor microarray (TMA).
| Variable | GLS H-score median (25th percentile, 75th percentile) | p-value* | |||||
|---|---|---|---|---|---|---|---|
| n | Values | n | Values | n | Values | ||
| Negative | Positive | ||||||
| ER | 65 | 88.3 (50.5, 120.1) | 213 | 50.1 (26.7, 74.5) | <0.0001 | ||
| PR | 97 | 75.2 (40.1, 111.6) | 167 | 50.2 (26.0, 74.5) | 0.0001 | ||
| HER-2/neu | 120 | 63.4 (36.4, 89.7) | 38 | 66.2 (24.8, 107.9) | 0.8059 | ||
| ER+/PR+/HER- | 53 | 81.9 (27.7, 112.9) | 103 | 63.1 (34.0, 87.6) | 0.1198 | ||
| Nodal status | 166 | 54.4 (26.2, 89.2) | 119 | 58.0 (34.0, 90.9) | 0.2926 | ||
| Caucasian | African American | ||||||
| Race | 230 | 51.7 (27.7, 87.2) | 59 | 81.9 (42.7, 108.4) | 0.0085 | ||
| Grade 1 | Grade 2 | Grade 3 | |||||
| Tumor grade | 67 | 51.9 (22.7, 71.6) | 126 | 46.5 (24.8, 74.5) | 78 | 89.6 (54.1, 117.9) | <0.0001** |
| T0/1 | T2 | T3/4 | |||||
| Tumor stage | 152 | 49.9 (26.1, 82.2) | 106 | 58.4 (33.2, 97.5) | 33 | 75.8 (47.6, 110.4) | 0.0117** |
*
From Wilcoxon Rank Sum test for Hormone Receptor Status and Kruskal-Wallis test for Tumor Grade and Tumor Stage.
**
The difference between Grade 1 and 3 was significant (p <0.0001) and Grade 2 and 3 (p <0.0001). The difference between T0/1 and T3/4 was significant (p = 0063).