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. 2019 May 31;6(2):MMT20. doi: 10.2217/mmt-2018-0010

Table 5. . Antimelanoma therapy pre- and post-dendritic cell vaccine.

Other therapies received Stage 3 NMD (n = 18) Stage 4 NMD (n = 30) Stage 4 MD (n = 24)
  Pre Post Pre Post Pre Post
Metastasectomy (ies) locoregional 18 3 2 1 9 2
Metastasectomy (ies) distant 0 6 23 17 11 7
RT (not brain) 7 4 6 6 7 6
Brain RT 0 2 6 5 7 8
Chemotherapy 8 4 14 7 19 16
IL-2 6 2 15 7 13 2
IFN-α 9 1 10 1 11 1
GM-CSF 5 3 11 4 8 1
Anti-VEGF 0 1 1 1 4 2
Anti-VEGF-TKI 0 0 0 0 1 4
Vaccine 2 2 7 3 0 1
Anti-BRAF 0 0 0 2 0 1
Anti-BRAF + Anti-MEK 0 0 0 0 0 1
Anti-CTLA4 0 0 0 4 1 5
Anti-PD1 0 0 0 1 0 0
None and no PD 0 6 0 3 0 2

CSF: Cerebrospinal fluid; LR: Locoregional; MD: Measurable disease; NMD: No measurable disease; PD: Progressive disease; PD1: Programmed death molecule 1; RT: Radiation therapy; TKI: Tyrosine kinase inhibitor.