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Ring-opening of aziridines 3.a
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Reaction conditions: 3 (0.2 mmol), A26 Resin – HF (5 equiv HF), DCE (0.4 mL), room temperature, 3h. All yields are for the isolated product.
Numbers in parenthesis are regioisomeric ratio determined by 19F NMR.
starting aziridine are mixture of cis- and trans-isomers.
