Table 2.
Cox regression analyses of the factors associated with the 1-year recurrence rate in patients with a single small HCC
| Univariable analysis |
Multivariable analysis |
|||||
|---|---|---|---|---|---|---|
| Variable | HR | P | 95% CI | HR | P | 95% CI |
| Sex | 0.540 | 0.053 | 0.289–1.009 | |||
| Age | 0.997 | 0.812 | 0.971–1.024 | |||
| Alcoholism history | 1.889 | 0.013 | 1.143–3.120 | 1.813 | 0.024 | 1.081–3.039 |
| WBC | 1.049 | 0.424 | 0.934–1.178 | |||
| NLR | 1.028 | 0.420 | 0.961–1.100 | |||
| PLT | 0.997 | 0.299 | 0.992–1.002 | |||
| ALT | 1.001 | 0.498 | 0.998–1.003 | |||
| GGT | 1.008 | 0.000 | 1.004–1.012 | 1.006 | 0.003 | 1.002–1.010 |
| TBIL | 1.005 | 0.334 | 0.995–1.015 | |||
| TP | 0.970 | 0.050 | 0.941–1.000 | 0.960 | 0.014 | 0.929–0.992 |
| HBV-DNA | 1.439 | 0.186 | 0.839–2.468 | |||
| PT | 1.042 | 0.387 | 0.949–1.143 | |||
| AFP | 1.809 | 0.019 | 1.250–3.359 | 2.073 | 0.006 | 1.232–3.487 |
| CD8+ T lymphocytes | 0.998 | 0.048 | 0.996–1.000 | |||
HR, hazard ratio; 95% CI, 95% confidence interval; WBC, white blood cells; NLR, neutrophil–lymphocyte ratio; PLT, platelets; ALT, alanine transaminase; GGT, γ-glutamyl transpeptidase; TBIL, total bilirubin; TP, total proteins; HBV, hepatitis B virus; PT, prothrombin time; AFP, α-fetoprotein.