FIG 1.

(A) Objective response rate (ORR) per independent radiology review committee (IRC) and investigator at end of monotherapy, after two combination cycles, and at end of therapy. Total number of patients was 51. (B) Change in target lesion per IRC in response-evaluable patients at end of treatment. Horizontal line indicates 50% reduction consistent with 2007 International Working Group response criteria. Three patients had greater than 50% reduction in target lesion burden but were considered to have new or ¹⁸F-labeled fluorodeoxyglucose–positron emission tomography (FDG-PET) positive lesions by the IRC. CR, complete remission; INV, investigator assessment; PR, partial remission.