Table 1. Baseline characteristics of women of childbearing age separated by pregnancy during the follow-up period.
| Baseline Characteristics of Women | All (n = 7,966) | Pregnant during followup (n = 249) | Not pregnant during followup (n = 7,717) | P Value |
|---|---|---|---|---|
| Age at transplant (years)* | 33 (8) | 27 (6) | 34 (8) | <0.0001 |
| <0.0001 | ||||
| 15–19 | 6.8 | 10.8 | 6.7 | |
| 20–24 | 8.3 | 19.3 | 7.9 | |
| 25–29 | 13.9 | 28.9 | 13.4 | |
| 30–34 | 18.8 | 26.1 | 18.6 | |
| 35–45 | 52.2 | 14.9 | 53.4 | |
| Race | <0.0001 | |||
| Black | 33.1 | 28.9 | 33.2 | |
| Hispanic | 18.7 | 29.7 | 18.3 | |
| White | 39.9 | 36.1 | 40.1 | |
| Other/unknown | 8.3 | 5.2 | 8.4 | |
| Donor type | 0.0363 | |||
| Living | 28.3 | 34.1 | 28.1 | |
| Deceased | 71.7 | 65.9 | 71.9 | |
| Transplant year | 0.5546 | |||
| 2005 | 16.2 | 13.3 | 16.3 | |
| 2006 | 15.8 | 16.9 | 15.8 | |
| 2007 | 14.5 | 15.3 | 14.5 | |
| 2008 | 13.0 | 14.5 | 13.0 | |
| 2009 | 13.8 | 14.9 | 13.7 | |
| 2010 | 13.6 | 10.4 | 13.7 | |
| 2011 | 13.0 | 14.9 | 13.0 | |
| Cause of ESKD | 0.0003 | |||
| Cystic/hereditary | 4.6 | 6.4 | 4.6 | |
| Diabetes mellitus | 18.5 | 8.8 | 18.9 | |
| GN/vasculitis | 41.8 | 51.0 | 41.5 | |
| Hypertension/LVD | 14.1 | 12.1 | 14.2 | |
| Other | 20.9 | 21.7 | 20.9 | |
| Immunosuppression at time of transplant | ||||
| Cyclosporine/tacrolimus | 92.8 | 96.0 | 92.7 | 0.0466 |
| Mycophenolate | 89.4 | 88.4 | 89.5 | 0.5698 |
| Sirolimus | 6.0 | 7.2 | 6.0 | 0.4175 |
| Prednisone/steroids | 92.4 | 91.2 | 92.5 | 0.4430 |
| GFR at six months after transplantation (ml/min/1.73 m2)* | 61.3 (23.3) | 65.8 (23.2) | 61.2 (23.3) | 0.0021 |
| <0.0001 | ||||
| ≥60 | 45.6 | 57.8 | 45.2 | |
| <60 | 47.8 | 41.4 | 48.0 | |
| Missing creatinine value | 6.6 | 0.8 | 6.8 | |
| Duration of dialysis (years) | 0.0152 | |||
| <3 | 48.3 | 55.8 | 48.0 | |
| ≥3 | 51.7 | 44.2 | 52.0 | |
| Comorbidities | ||||
| Diabetes mellitus | 17.7 | 10.0 | 18.0 | 0.0013 |
| Hypertension | 72.6 | 76.3 | 72.4 | 0.1782 |
| Congestive heart failure | 5.5 | 6.4 | 5.5 | 0.5328 |
| Region | 0.3679 | |||
| Northeast | 19.1 | 20.9 | 19.1 | |
| South | 39.0 | 33.3 | 39.2 | |
| Midwest | 23.2 | 23.7 | 23.1 | |
| West | 18.7 | 22.1 | 18.6 | |
| Unknown | 0.1 | 0.0 | 0.1 | |
| Prior transplant recipient | 17.8 | 18.5 | 17.8 | 0.7901 |
| Died during follow-up | 5.5 | 1.2 | 5.6 | 0.0027 |
| Graft failure during follow-up | 15.5 | 13.3 | 15.6 | 0.3163 |
| Conception year | ||||
| Year 1 | 26.9 | |||
| Year 2 | 42.6 | |||
| Year 3 | 43.0 |
*Reported in mean (standard deviation); ESKD, end stage kidney disease; GN, glomerulonephritis; LVD, large vessel disease; GFR, glomerular filtration rate