Table 3. Cortical morphology and slow wave activity topography.
Associations between Frontal/Occipital ratio (F/O-ratio) of slow wave activity and cortical morphological measures were calculated with Spearman correlations and partial correlations controlling for ‘age at T1 or T2’ (n=13 for T1, n=14 for T2). False discovery rate (FDR) analysis was performed. Significant associations (p<0.05) are presented in bold. With exclusion of the one subject with the T2 assessment only, results were overall consistent (n=13). Relationships with F/O-ratio at T2: Surface area: Spearman correlation Rho= 0.09, p=0.78, pFDR=0.89; partial correlation: Rho= −0.01, p=0.97, pFDR=0.97. Gray matter volume: Spearman correlation Rho=0.24, p=0.44, pFDR=0.78; partial correlation: Rho=0.21, p=0.52, pFDR=0.84. Cortical thickness: Spearman correlation Rho= 0.36, p=0.22, pFDR=0.66; partial correlation: Rho=0.41, p=0.18, pFDR=0.66. Curvature: Spearman correlation Rho= −0.14, p=0.64, pFDR=0.85; partial correlation: Rho= −0.38, p=0.22, pFDR=0.66.
| Cortical markers at T2 | Surface area (mm2) | Gray matter volume (mm3) | Cortical thickness (mm) | Curvature | |||||
|---|---|---|---|---|---|---|---|---|---|
| Spearman correlation |
Partial correlation |
Spearman correlation |
Partial correlation |
Spearman correlation |
Partial correlation |
Spearman correlation |
Partial correlation |
||
| Slow wave activity topography | F/O-ratio at T1 | Rho=0.30 p=0.32 pFDR=0.61 |
Rho=0.15 p=0.64 pFDR=0.85 |
Rho=0.12 p=0.70 pFDR=0.86 |
Rho=0.05 p=0.87 pFDR=0.93 |
Rho=−0.35 p=0.25 pFDR=0.61 |
Rho=−0.44 p=0.16 pFDR=0.61 |
Rho=0.55 p=0.05 pFDR=0.61 |
Rho=0.27 p=0.39 pFDR=0.61 |
| F/O-ratio at T2 | Rho=0.24 p=0.42 pFDR=0.61 |
Rho=0.07 p=0.82 pFDR=0.93 |
Rho=0.37 p=0.20 pFDR=0.61 |
Rho=0.28 p=0.35 pFDR=0.61 |
Rho=0.27 p=0.35 pFDR=0.61 |
Rho=0.36 p=0.23 pFDR=0.61 |
Rho=0.02 p=0.93 pFDR=0.93 |
Rho=−0.31 p=0.31 pFDR=0.61 |
|