Table 1.
Distribution of baseline characteristics according to treatment with DDAVP
| Baseline characteristic | All patients (n=1639) | Patients Treated with DDAVP (n=143) | Control patients (n= 1496) | P value |
|---|---|---|---|---|
| Mean age, y (mean, ±SD) | 55 ±15 | 55 ± 14 | 55 ± 15 | 0.81 |
| Male, n (%) | 538 (33) | 43 (30) | 495 (33) | 0.50 |
| Medical History | ||||
| Hypertension, n (%) | 768 (47) | 79 (55) | 689(46) | 0.06 |
| Antiplatelet use, n (%) | 196 (12) | 42 (29) | 154 (10) | <0.001 |
| NSAID use, n (%) | 94 (6) | 18 (13) | 76 (5) | <0.001 |
| Clinical Presentation | ||||
| Sentinel bleed, n (%) | 315 (21) | 34 (27) | 281 (21) | 0.10 |
| Seizures, n (%) | 178 (11) | 16 (12) | 162 (11) | 0.89 |
| LOC, n (%) | 641 (40) | 51 (36) | 590 (40) | 0.39 |
| Hunt and Hess grade, n (%) | <0.001 | |||
| I | 384 (24) | 13 (9) | 371 (25) | |
| II | 340 (21) | 44 (31) | 296 (20) | |
| III | 410 (25) | 32 (23) | 378 (25) | |
| IV | 231 (14) | 23 (16) | 208 (14) | |
| V | 269 (16) | 30 (21) | 239 (16) | |
| Imaging | ||||
| Proven aneurysm, n (%) | 1245 (87) | 112 (85) | 1133 (87) | 0.65 |
| Aneurysm >10mm, n (%) | 239 (17) | 11 (8) | 228 (17) | 0.008 |
| Intracerebral Hematoma, n (%) | 275 (17) | 18 (13) | 257 (17) | 0.17 |
| Modified Fisher, n (%) | 0.002 | |||
| 1 | 524 (32) | 47 (24) | 477 (33) | |
| 2 | 197 (12) | 16 (8) | 181 (13) | |
| 3 | 571 (35) | 74 (38) | 497 (35) | |
| 4 | 326 (20) | 57 (29) | 269 (19) | |
| Treatment | ||||
| Platelet transfusion | 87 (5) | 87 (44) | 0 (0) | <0.001 |
| Median time from admission to diagnosis, days (IQR) | 0 (0) | 0 (0) | 0 (0) | |
LOC: Loss of consciousness