Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Aug 9;10:3355. doi: 10.1038/s41467-019-11335-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 5 — More genes are differentially expressed between schizophrenia and control subjects if they died during the night. a Table showing number of DE genes during day or night at various significance cutoffs. A permutation test was used to return corrected p-values and Storey’s q value was used to correct for multiple testing. b Venn diagram indicating overlap in genes that are DE at p < 0.05 in schizophrenia at night and during the day. Many genes that have previously been identified as being disrupted in schizophrenia are DE only at night (e.g., BDNF, PVALB, SST). c The pathways represented by the genes that are DE only at night are related to oxidative phosphorylation and mitochondrial dysfunction. The pathways represented by the genes that are trending towards DE only during the day relate to immune function. For the genes that are DE both during the day and night, the top pathways are related to immune function and Cdc42 signaling