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. 2019 Aug 9;9:11570. doi: 10.1038/s41598-019-48097-1

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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En face OCT and cross sectional OCT of a right eye that had postoperative microcysts. (A) The central 3 × 3 mm macula was divided into 5 Early Treatment for Diabetic Retinopathy Study (ETDRS) areas in this en face image at the superficial capillary plexus level. The center subfield was 1 mm in diameter. The white dotted line indicates the area of ILM being peeled. White arrows indicate dissociated optic nerve fiber layer within the area of denuded ILM. (B) En face view at the deep capillary plexus of the same eye in center 3 × 3 mm of (A) showed microcystic formations in the nasal subfield that extend to the superior and inferior subfields. The area of each cluster and their density of microcyst were calculated as in the irregular circle. (C) In this cross sectional OCT, the microcysts appeared as multiple spindle shaped hollow cavity in the inner nuclear layer. Note that the vertical and horizontal scale lines represent 200 μm. The yellow rectangle area was magnified as shown in (D). (D) The width and length of microcysts determined by a built-in function of the Avanti RTVue XR show that the “spindle-shaped” microcyst actually approximates a spheroid shape (71 × 74 μm) after adjusting the vertical and horizontal scales.