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. 2019 Aug 5;12:6145–6156. doi: 10.2147/OTT.S209784

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© 2019 Zheng et al.

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OGFR was associated with si-LINC00673-mediated inhibition of proliferation and metastasis in EOC.

Notes: (A) The expression of OGFR was detected after transfection with the OGFR-siRNAs. (B) The expression of OGFR was measured after co-transfection with si-OGFR and si-LINC00673. (C) RTCA was performed to assess the proliferation of the transfected cells. (D) Transwell assays were conducted to evaluate the invasion and migration capacities of HO8910 cells. All results are shown as the means ± SD and are representative of three independent experiments (**P<0.01; ***P<0.001; ****P<0.0001 by Student’s t-test).

Abbreviations: KD, LINC00673-knockdown lentivirus cells; NC, LINC00673-negative control lentivirus cells; EOC, epithelial ovarian cancer; RTCA, real-time cellular analysis; OGFR, opioid growth factor receptor.