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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: J Thromb Haemost. 2019 Jun 20;17(8):1384–1396. doi: 10.1111/jth.14521

Figure 3. Influence of SCARA5 deficiency on VWF and FVIII in vivo.

Figure 3

Plasma VWF:Ag levels (A), VWFpp (B), and VWFpp/VWF:Ag (C)) were measured in C57Bl/6 SCARA5 KO mice as compared with wild-type C57Bl/6 mice. VWF/SCARA5 DKO mice were generated and VWF clearance was measured in comparison with VWF KO mice. (D) Clearance of murine plasma-derived VWF in the absence of murine SCARA5 expression. (E) Clearance of human plasma-derived VWF in the absence of murine SCARA5 expression.