Table 5.
Odds Ratios (95% Cl) of incident hs-cTnT≥14 ng/L and NT-proBNP≥100 pg/mL at MESA Exam 3 according to estimated sodium intake quintile.
| Q1 (0.2-1.3 g/d) |
Q2 (1.3-1.8 g/d) |
Q3 (1.8-2.4 g/d) |
Q4 (2.4-3.2 g/d) |
Q5 (3.2-9.9 g/d) |
|
|---|---|---|---|---|---|
| hs-cTnT≥14 ng/L | 43 (7%) | 44 (7%) | 40 (6.8%) | 56 (8.9%) | 54 (8.9%) |
| N | 611 | 630 | 593 | 631 | 607 |
| Model 1 | 1.11 (0.71, 1.73) | Ref=1 | 0.96 (0.61, 1.52) | 1.20 (0.79, 1.84) | 1.31 (0.85, 2.02) |
| Model 2 | 1.14 (0.72, 1.80) | Ref=1 | 0.98 (0.61, 1.55) | 1.17 (0.76, 1.80) | 1.25 (0.81, 1.95) |
| Model 3 | 1.15 (0.73, 1.81) | Ref=1 | 0.98 (0.62, 1.57) | 1.16 (0.75, 1.80) | 1.24 (0.79, 1.93) |
| NT -proBNP≥100 pg/mL | 103 (18.3%) | 112 (19.7%) | 119 (19.8%) | 112 (17.9%) | 105 (15.6%) |
| N | 563 | 569 | 601 | 627 | 675 |
| Model 1 | 0.86 (0.63, 1.17) | Ref=1 | 1.20 (0.89, 1.63) | 1.01 (0.75, 1.38) | 1.02 (0.75, 1.39) |
| Model 2 | 0.89 (0.65, 1.23) | Ref=1 | 1.23 (0.90, 1.67) | 1.05 (0.77, 1.44) | 1.10 (0.80, 1.51) |
| Model 3 | 0.90 (0.65, 1.23) | Ref=1 | 1.22 (0.89, 1.66) | 1.04 (0.76, 1.42) | 1.10 (0.80, 1.52) |
Model 1: age and sex.
Model 2: Model 1 plus race/ ethnicity, body mass index, smoking status, alcohol consumption, total cholesterol, high-density lipoprotein cholesterol, triglycerides, estimated glomerular filtration rate, lipid-lowering medication use, blood pressure–lowering medication, and history of diagnosed diabetes.
Model 3: Model 2 plus systolic BP