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. Author manuscript; available in PMC: 2020 Sep 1.
Published in final edited form as: J Geriatr Oncol. 2019 Feb 11;10(5):733–741. doi: 10.1016/j.jgo.2019.02.003

Table 3.

Univariate (A) and multivariate (B) Cox regression analysis for OS of all patients.

(A)
Variables Level HR (95% CI) p
Gender (ref = Male) Female 1.25 (0.87–1.80) 0.22
Race (ref = White) Others 1.47 (0.93–2.32) 0.10
PS ECOG (ref=0–1) ≥ 2 1.86 (1.10–3.17) 0.019
Primary site (ref = Colon) Rectum 0.58 (0.34–0.98) 0.040
Histology Differentiation (ref = Well/Moderate) Poorly differentiation 2.03 (1.27–3.25) 0.003
Liver metastasis (ref = No) Yes 0.84 (0.55–1.29) 0.42
Peritoneum metastasis (ref = No) Yes 1.52 (0.97–2.39) 0.07
Lung metastasis (ref = No) Yes 1.14 (0.74–1.76) 0.56
Prior Operation (ref = No) Yes 0.80 (0.55–1.17) 0.25
Max2, per 1SD (SD = 0.046) increase Female 1.10 (0.93–1.30) 0.27
Age at Diagnosis, per 5 years old increase 1.17 1.01–1.34) 0.034
CIRS-G severity index 0.99 (0.81–1.21) 0.94
Number of CIRS-G score 3 (ref=0) 1 1.02 (0.68–1.54) 0.179
>=2 0.64 (0.39–1.06) 0.085
Number of CIRS-G score 4 (ref=0) >=1 2.16 (1.15–4.05) 0.014
HEART (ref=0) 1–4 0.89 (0.61–1.31) 0.563
VASCULAR (ref=0) 1–4 0.75 (0.49–1.14) 0.177
HEMATOPOIETIC (ref=0) 1–4 1.78 (0.72–4.41) 0.204
RESPIRATORY (ref=0) 1–4 1.25 (0.87–1.79) 0.224
EENT_LARYNX (ref=0) 1–4 0.94 (0.65–1.38) 0.767
UPPER_GI (ref=0) 1–4 1.27 (0.87–1.85) 0.222
LOWER_GI (ref=0) 1–4 0.83 (0.56–1.21) 0.325
LIVER (ref=0) 1–4 0.72 (0.40–1.28) 0.262
RENAL (ref=0) 1–4 1.24 (0.79–1.94) 0.352
GENITOURINARY (ref=0) 1–4 0.94 (0.66–1.35) 0.730
MUSCULOSKELETAL (ref=0) 1–4 1.02 (0.70–1.48) 0.928
NEUROLOGICAL (ref=0) 1–4 0.97 (0.47–2.00) 0.939
ENDOCRINE (ref=0) 1–4 0.73 (0.51–1.04) 0.076
PSYCHIATRIC_ILLNESS (ref=0) 1–4 1.22 (0.79–1.87) 0.366
(B)
Variables Level HR (95% CI) p
PS ECOG (ref=0–1) 0–1
≥ 2 2.28 (1.33–3.92) 0.003
Primary site (ref=colon) Rectum 0.47 (0.28–0.81) 0.006
Histology differentiation (ref=well/moderate) Poorly differentiation 2.03 (1.27–3.25) 0.003
Age, per 5 years old increase 1.20 (1.04–1.39) 0.012