Table 1.
Characteristics of the 2 groups: mean±SD / frequency count
| Control (n=109) | HIV (n=57) | p-value* | |
|---|---|---|---|
| Demographics | |||
| N (men/women) | 64/45 | 40/17 | 0.15 |
| Age (years) | 51.7±14.3 | 53.3±6.9 | 0.44 |
| Handedness (Right/Left or Both) | 97/12 | 52/5 | 0.22 |
| Ethnicity♩ (Caucasian/African American/Asian/Other) | 53/29/23/4 | 24/30/1/2 | 0.0005 |
| Body Mass Index (BMI) | 26.5±4.8 | 25.3±4.4 | 0.13 |
| Systolic Blood Pressure | 128.1±19.6 | 123.8±15.3 | 0.17 |
| Diastolic Blood Pressure | 77.8±12.3 | 75.8±10.8 | 0.32 |
| Heart Rate | 65.8±10.9 | 69.3±14.8 | 0.10 |
| Education (years) | 15.7±2.5 | 13.5±2.6 | <0.0001 |
| Socioeconomic Status# (SES) | 29.1±14.6 | 40.7±15..2 | <0.0001 |
| Smoker (never/past or current) | 93/9 | 34/20 | <0.0001 |
| Nicotine (daily) | 1.0±2.9 | 2.8±5.1 | 0.07 |
| Lifetime Alcohol (kg) | 33.6±56.7 | 76.3±78.8 | <0.0001 |
| Diabetes (yes/no) | 2/59 | 6/34 | 0.03 |
| Beck Depression Index (BDI) | 3.3±4.2 | 10.8±8.7 | <0.0001 |
| Dementia Rating Scale (DRS, total raw score) | 139.5±3.0 | 135.7±5.2 | <0.0001 |
| HIV-Related Variables | |||
| Global Assessment of Functioning (GAF) | 84.3±6.1 | 71.7±10.7 | <0.0001 |
| VACS Index | 14.1±13.4 | 31.1±17.5 | <0.0001 |
| Hepatitis C Virus (HCV, positive/negative) | 3/106 | 21/36 | <0.0001 |
| HIV onset age (years) | - | 36.6±8.6 | na |
| HIV duration (years) | - | 16.7±7.8 | na |
| Viral Load (log copies/mL) | - | 2.1±1.1 | na |
| CD4 cell count (100/mm3) | - | 569.6±267.0 | na |
| CD4 cell count nadir (100/mm3) | - | 195.3±178.8 | na |
| AIDS-defining event (yes/no) | - | 30/27 | na |
| ART (yes/no) | - | 50/7 | na |
| Nucleoside Reverse Transcriptase Inhibitors (NRTI, 0/1/2) | - | 9/38/10 | na |
| Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTI, 0/1 | - | 43/14 | na |
| Protease Inhibitors (PI, 0/1/2) | - | 29/11/17 | na |
| Fusion Inhibitors (FI, 0/1) | - | 49/8 | na |
t-tests used on continueous variables; X2 used on nominal variables (e.g., handedness)
♩
self-defined: Other = Multiracial or Unknown
#
lower score = higher status