Fig. 1. Non-invasive molecular imaging modalities for vaccine research. (A) Imaging modalities for optical imaging (fluorescence, bioluminescence imaging). (B) Imaging modalities for medical imaging (PET, SPECT, CT, MRI, US). (C) In vivo sensitivity and resolution of each imaging modality. (D) In vivo penetration and resolution of each imaging modality. BLI, bioluminescence imaging; GFP, green fluorescent protein; i.p., intraperitoneal injection; i.v., intravenous injection; MR, magnetic resonance; NIR, near-infrared; PET, positron emission tomography; SPECT, single photon emission computed tomography; US, ultrasonography.
