Table 3.
Concentration (µg/mL) | Percentage α-glucosidase inhibition | IC50 (µg/mL) | |
---|---|---|---|
Glm | 1,000 | 77.00±0.15 | 49.52 |
500 | 69.26±1.55 | ||
250 | 65.89±0.49 | ||
125 | 58.36±0.71 | ||
62.5 | 51.47±0.42 | ||
GN | 1,000 | 83.53±0.20*** | 21.30 |
500 | 78.62±0.17*** | ||
250 | 73.42±0.11*** | ||
125 | 66.20±0.15** | ||
62.5 | 61.35±0.18*** |
Notes: Values represent means ± SD., **P<0.01, ***P<0.001 compared to Glm.
Abbreviations: Glm, glimepiride; GN, Glm nanosuspension.