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. 2019 Aug 6;12:6203–6216. doi: 10.2147/OTT.S213833

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© 2019 Luo et al.

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Overexpression of ELMO1-AS1 inhibited HCC cell migration and invasion in vitro. Wound healing assay showed that the migratory potential of SMMC-7721 (A) and HepG2 (B) cells were significantly reduced in the ELMO1-AS1-transfected group than in the control-transfected group. Transwell migration assay showed that the number of migrated SMMC-7721 (C) and HepG2 (E) cells was significantly lower in the ELMO1-AS1-transfected group than in the control-transfected group. Transwell invasion assay showed that the number of invaded SMMC-7721 (E) and HepG2 (F) cells was significantly lower in the ELMO1-AS1-transfected group than in the control-transfected group. ** and *** represent P<0.01 and P<0.001, respectively.

Abbreviation: HCC, hepatocellular carcinoma.