Table 3.
Variables | Multivariate analysis for OS | Multivariate analysis for CSS | ||||
---|---|---|---|---|---|---|
HR | 95% CI | p | HR | 95% CI | p | |
Age | ||||||
65–75 years | 1 (Referent) | 1 (Referent) | ||||
>75 years | 1.373 | 0.954–1.977 | 0.088 | 1.231 | 0.775–1.955 | 0.378 |
Gender | ||||||
Male | 1 (Referent) | 1 (Referent) | ||||
Female | 1.028 | 0.678–1.557 | 0.898 | 0.939 | 0.571–1.544 | 0.803 |
Race | ||||||
White | 1 (Referent) | 1 (Referent) | ||||
Black | 1.367 | 0.726–2.572 | 0.333 | 1.333 | 0.621–2.859 | 0.460 |
Other | 1.598 | 0.782–3.269 | 0.199 | 1.767 | 0.777–4.018 | 0.175 |
Marital status | ||||||
Married | 1 (Referent) | 1 (Referent) | ||||
Unmarried | 1.228 | 0.852–1.770 | 0.271 | 1.417 | 0.906–2.217 | 0.127 |
Year of diagnosis | ||||||
1973–2009 | 1 (Referent) | 1 (Referent) | ||||
2010–2015 | 0.931 | 0.634–1.365 | 0.714 | 1.027 | 0.638–1.651 | 0.913 |
Tumor site | ||||||
Head | 1 (Referent) | 1 (Referent) | ||||
Body/tail | 1.104 | 0.734–1.661 | 0.635 | 0.872 | 0.538–1.415 | 0.580 |
Overlap | 1.226 | 0.692–2.171 | 0.485 | 0.859 | 0.422–1.749 | 0.676 |
Other | 1.709 | 0.784–3.729 | 0.178 | 1.758 | 0.773–3.997 | 0.178 |
Histological grade | ||||||
Well/moderately | 1 (Referent) | 1 (Referent) | ||||
Poorly/undifferentiated | 3.062 | 2.118–4.425 | 0.000 | 3.641 | 2.351–5.640 | 0.000 |
Tumor size | ||||||
≤4 cm | 1 (Referent) | 1 (Referent) | ||||
>4 cm | 0.862 | 0.568–1.308 | 0.485 | 0.790 | 0.476–1.310 | 0.361 |
Unknown | 0.798 | 0.463–1.375 | 0.416 | 0.812 | 0.423–1.558 | 0.531 |
Primary site surgery | ||||||
No | 1 (Referent) | 1 (Referent) | ||||
Yes | 0.392 | 0.252–0.612 | 0.000 | 0.362 | 0.206–0.637 | 0.000 |
Note: Variables with univariate analysis p<0.1 underwent further multivariate analysis.
Abbreviations: OS, overall survival; CSS, cancer-specific survival; PSM, propensity score matching.