Table 5.
Vaccine target candidates for M. pneumoniae identified by Vaxign. TMHMM, transmembrane propeller prediction software.
| target | ID | name | location SurfG+ | adhesin probability | no. predicted epitopes | TMHMM | protein length (aa) | SignalP | gene | molecular weight (DA) UniProt |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | WP_010874999.1 | Mycoplasma specific lipoprotein, type 3 | PSE | 0.529 | 5 | 0 | 279 | yes 25–26 | MPN_642 | 31 287 |
| 2 | WP_014574866.1 | hypothetical lipoprotein | PSE/outer membrane | 0.557 | 16 | 0 | 524 | no | MPN_084 | 59 553 |
| 3 | WP_010874581.1 | pro-lipoprotein diacylglyceryl transferase | cytoplasmic membrane | 0.578 | 9 | 7 | 389 | no | MPN_XXX (Igt) | 44 596 |
| 4 | WP_010874862.1 | uncharacterized lipoprotein MPN_506 | PSE/cytoplasmic membrane | 0.618 | 19 | 0 | 793 | yes 24–25 | MPN_506 | 87 494 |
| 5 | WP_014325486.1 | uncharacterized protein | PSE/outer membrane | 0.667 | 16 | 0 | 793 | yes 24–25 | MPNE_0422 | 87 951 |
| 6 | WP_014325517.1 | uncharacterized lipoprotein MPN_408 | PSE | 0.606 | 15 | 0 | 760 | yes 28–29 | MPN_408 | 83 344 |
| 7 | WP_014325659.1 | uncharacterized lipoprotein MG440 | PSE | 0.536 | 7 | 0 | 277 | yes 26–27 | MPN_646 | 31 097 |
| 8 | WP_014325660.1 | uncharacterized lipoprotein MG439 homologue 1 | extracellular | 0.543 | 5 | 1 | 290 | yes 28–29 | MPN_647 | 31 823 |