Table 2.
Relationship of WTAP expression and clinicopathologic characteristics of HGSOC patients
| Variable | Total | WTAP expression | ||
|---|---|---|---|---|
| Low (n=10) | High (n=20) | P-value | ||
| Age (years) | 0.431 | |||
| <60 | 21 | 6 (7) | 15 (14) | |
| ≥60 | 9 | 4 (3) | 5 (6) | |
| BMI | 0.689 | |||
| <24 | 22 | 11 (15.2) | 11 (18.8) | |
| ≥24 | 8 | 5 (4.3) | 3 (3.7) | |
| Tumor size (cm) | 0.675 | |||
| <6 | 7 | 3 (3.7) | 4 (3.3) | |
| ≥6 | 23 | 13 (12.3) | 10 (10.7) | |
| Stage | 0.071 | |||
| I/II | 8 | 6 (3.7) | 2 (4.3) | |
| III/IV | 22 | 8 (10.3) | 14 (11.7) | |
| Grade of differentiation | 0.675 | |||
| G1 | 23 | 13 (12.3) | 10 (10.7) | |
| G2/G3 | 7 | 3 (3.7) | 4 (3.3) | |
| Lymph node metastasis | 0.013* | |||
| NO | 15 | 11(7.5) | 4 (7.5) | |
| YES | 15 | 4(7.5) | 11 (7.5) | |
| Volume of ascites (mL) | 0.260 | |||
| <500 | 20 | 9 (10.7) | 11 (9.3) | |
| ≥500 | 10 | 7 (5.3) | 3 (4.7) | |
| CA125 (U/mL) | 0.257 | |||
| <500 | 11 | 4 (5.9) | 7 (5.1) | |
| ≥500 | 19 | 12 (10.1) | 7 (8.9) | |
Notes: *P<0.05. P-values were two-tailed and based on the Fisher’s exact test; Values in brackets represent the expected count.
Abbreviation: HGSOC, high-grade serous ovarian carcinoma.