Table 2.
Adverse events occurring in HAM/TSP patients during HuMikβ1 trial.
| Group | Adverse event | Grade | Number of events |
|---|---|---|---|
| 0.5mg | pruritus | 1 | 1 |
| flu‐like syndrome | 1 | 1 | |
| hypotension | 1 | 1 | |
| hypokalemia | 1 | 1 | |
| tachycardia | 1 | 1 | |
| fever | 1 | 1 | |
| palpitation | 1 | 1 | |
| diarrhea | 1 | 1 | |
| infection | 2 | 1 | |
| decubitus ulcer | 2 | 1 | |
| limb edema | 2 | 1 | |
| substernal pain | 2 | 1 | |
| rash/desquamation 1 | 2 | 1 | |
| thrombosis 1 | 3 | 2 | |
| 1.0mg | headache, chills, fatigue | 1 | 1 |
| flu‐like symptoms | 1 | 2 | |
| paresthesias | 1 | 1 | |
| herpes labialis | 1 | 1 | |
| prolonged QTCB on EKG | 1 | 1 | |
| rash | 1 | 1 | |
| tooth abscess | 2 | 1 | |
| infection/UTI | 2 | 1 | |
| elevated ALT | 2 | 1 | |
| shoulder pain | 3 | 1 | |
| thrombosis | 3 | 1 | |
| 1.5 mg | bradycardia | 1 | 1 |
| low b12 | 1 | 1 | |
| elevated RSVP on echo | 1 | 1 | |
| contact dermatitis | 1 | 1 | |
| anemia | 1 | 1 | |
| vaginal spotting | 1 | 1 | |
| lymphopenia | 1 | 1 | |
| lymphopenia | 2 | 1 | |
| elevated troponin | 2 | 1 | |
| elevated troponin | 2 | 1 | |
| post dural puncture headache | 4 | 1 |
1
Post study