Table 2.
Bivariate and multivariate analysis on selected risk factors associated with blood culture proven neonatal sepsis at ATRH, NICU, May 2016 to April 2017
| Parameter | Culture proven sepsis | Univariate | Multivariate analysis | ||||
| yes | No | COR((%CI) | Pvalue | AOR (95% CI) | P value | ||
| Sex | Male | 57(29%) | 141(71%) | 1.1(0.93–1.27) | 0.27 | 1.405(0.769–2.568) | 0.234 |
| Female | 31(30%) | 74(70%) | |||||
| Mode of delivery |
C/S* | 24(22.7%) | 64(77.3%) | ||||
| SVD* | 64(24.6%) | 166(75.4%) | 1.41(0.83–2.38) | 0.67 | 1.11(0.565–2.199) | 0.755 | |
| Gestational age in weeks |
28–36 | 20(28.6%) | 49(71.4%) | 4.05(1.23–9.15) | 0.022 | 3.52(1.305–12.048) | 0.044 |
| 37–42 | 68(23%) | 180(77%) | |||||
| Place of delivery |
Home | 12(23.8%) | 35(76.2%) | 1.1(0.48–2.39) | 0.86 | 0.98(0.344–2.811) | 0.976 |
| Health facility |
66(25.8%) | 190(75.9) | 7yfgfs | ||||
| Birth weight | 1–2.49kg | 23(31.5%) | 50(68.5%) | 2.10(1.07–4.08) | 0.007 | 1.3(0.5–3.3) | 0.015 |
| 2.5–4kg | 55(24%) | 175(76%) | |||||
| Prolonged PROM* |
Yes | 33(35.8%) | 59(64.2%) | 1.12(1.01–1.4) | 0.048 | 2.31(0.94–5.65) | 0.007 |
| No | 55(26.1%) | 156(73.9%) | |||||
| Meconium stained liquor |
Yes | 19(30.2%) | 44(69.8%) | 1.10(0.90–1.34) | 0.067 | 1.9(0.74–4.77) | 0.013 |
| No | 69(22.8%) | 171(77.2%) | |||||
| Fifth minute Apgar score |
0–6 | 30(42.9%) | 40(57.1%) | 1.60(1.13–2.34) | 0.009 | 2.10(1.18–3.73) | 0.012 |
| 7–10 | 49(26.3%) | 137(73.7%) | |||||
| IAP* | Yes | 5(10%) | 45(90%) | ||||
| No | 83(32.8%) | 170(67.2%) | 1.23(1.07–1.4) | 0.013 | 3.30(1.122–9.708) | 0.03 | |
IAP*-Intrapartal antibiotic prophlaxis, PROM*- prolonged rupture of membrane, SVD*-Spontaneous vaginal delivery, C/S*cesarean