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. 2019 May 15;122(1):358–367. doi: 10.1152/jn.00173.2019

Fig. 3.

Fig. 3.

A: means ± SE of 24-h mean arterial blood pressure (ABP) and heart rate before and after unilateral clipping of the left renal artery. *P < 0.05 vs. average baseline (1-way ANOVA and paired t-tests with layered Bonferroni correction). B: means ± SE and individual data points of changes (Δ) in mean ABP in response to ganglionic blocker hexamethonium (30 mg/kg ip). *P < 0.05 vs. day 0 (paired t-test). C: images of 2-kidney, 1-clip (2K1C) unclipped vs. clipped kidneys illustrate reduction in renal mass after unilateral clipping. Graph shows means ± SE and individual data points of renal mass in unclipped and clipped kidneys in 2K1C mice. *P < 0.05 vs unclipped. D: renal histology revealed the presence of damaged glomeruli (arrow, top) and renal casts (arrows, bottom) in clipped but not unclipped kidneys of 2K1C mice.