Fig. 6.

Digital images of immunofluorescence labeling for transient receptor potential vanilloid type 1 (TRPV1) and tyrosine hydroxylase in clipped kidneys of control, ipsilaterally denervated, and capsaicin (CAP)-treated (renal afferent denervated) mice. Note the presence of TRPV1- vs. tyrosine hydroxylase-positive fibers in the kidney of 2-kidney, 1-clip (2K1C) sham mice that were predominantly localized to the pelvis vs. cortex and medulla, respectively. However, both markers were absent in mice with ipsilateral renal denervation. Tyrosine hydroxylase-positive, but not TRPV1-positive, fibers were present in mice with selective renal afferent denervation. Arrows indicate positive-labeled terminals. Scale bar, 100 µm.