Figure 3.
Expression of Wnt signaling pathway- and EMT-related proteins in non-small cell lung cancer cells after KRT17 overexpression or knockdown. (A, B, and C) Western blot analysis for proteins relevant to the Wnt signaling pathway and EMT in A549-KRT17 (A), H1299-KRT17 (B), SE-MES-1-siKRT17 (C), and their control cells. GAPDH served as an internal control. (D, E, and F) Relative expression levels of proteins for each group are shown in the histogram. *P<0.05; **P<0.01.
Abbreviations: EMT, epithelial mesenchymal transition; NC, negative control cell; siNC, small interfering RNA negative control cell; siKRT17, small interfering RNA against keratin 17.