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. 2019 Aug 12;11:116. doi: 10.1186/s13148-019-0715-0

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Epigenetic inactivation of TFPI2, SOX17, GATA4, and FBN2 in normal oral mucosa and OSCC primary tissues. a Methylation status of TFPI2, SOX17, GATA4, and FBN2 in normal oral mucosa (n = 11) and b the methylation frequency of the four genes in OSCC primary tissues (n = 33). M = methylation signal; U = unmethylated signal; IVD = in vitro methylated DNA; ddH₂O = water control without DNA. The bar graph shows the MSP results of all primary samples