Table 4.

Preventive and therapeutic interventions that either were not included in our selected articles or were not explored enough.

Interventions	Target	Preventive/therapeutic
Increasing awareness of the risks associated with opioid (RX Awareness)	Public awareness	Preventive
Safe disposal	Drug diversion	Both
Controlled substance tracking and monitoring	Illegal buyers	Both
Needle exchange, case management, drug consumption room, social supply of drugs, heroin-assisted therapy	Opioid users	Therapeutic
Immunity from prosecution, naloxone over-the-counter or by prescription	Overdoses	Therapeutic

Each intervention is targeting a different sector of the opioid epidemic.